Bireticulol, a bioactive isocoumarin dimer from Streptomyces sp. Ayer, W.
Two 1H-naphtho [2, 3-c] pyranone metabolites from the fungus Paecilomyces variotii. Hald, B. Natural occurrence of the mycotoxin viomellein in barley and the associated quinone-producing penicillia. Wei, M.
A new dihydroisocoumarin with an isoprenyl group from the endophytic fungus Cephalosporium sp. Chen, M. Dihydroisocoumarin derivatives with antifouling activities from a gorgonian-derived Eurotium sp. Tetrahedron , , 70 , Wang, Q. Polyketides with antimicrobial activity from the solid culture of an endolichenic fungus Ulocladium sp. Fitoterapia , , 83 , Bi, Y. Four novel dihydroisocoumarin 3,4-dihydro-1Hbenzopyranone Glucosides from the fungus Cephalosporium sp.
Acta , , 87 , Oliveira, C. Dihydroisocoumarins produced by Xylaria sp.
Chinworrungsee, M. Halorosellins A and B, unique isocoumarin glucosides from the marine fungus Halorosellinia oceanica. Li, C. Lycopodiellactone, an unusual d-lactone-isochromanone from a Hawaiian plant-associated fungus Paraphaeosphaeria neglecta FT Cabras, A. Occurrence, isolation and biological activity of phytotoxic metabolites produced in vitro by Sphaeropsis sapinea , pathogenic fungus of Pinus radiata. Plant Pathol.
Tian, J-F. Cyclohexenones and isocoumarins from an endophytic fungus of Sarcosomataceae sp. Asian Nat. Elsebai, M. Isocoumarin derivatives from the marine-derived fungus Phoma sp. Kongsaeree, P. Antimalarial Dihydroisocoumarins Produced by Geotrichum sp.
Discussion Addendum for: Lithium Amides as Homochiral Ammonia Equivalents for Conjugate Additions to α,β-Unsaturated Esters: Asymmetric Synthesis of. The resulting mixture was heated at reflux (oil bath temperature 50–55 °C) for 1 h 2,8-Nonanedione is a useful synthetic intermediate for the synthesis of . Jäger, V.; Viehe, H. G. in Houben-Weyl, Methoden der Organischen Chemie, Vol.
Kokubun, T. Dihydroisocoumarins and a tetralone from Cytospora eucalypticola. Phytochemistry , , 62 , Ye, Y-Q. Isocoumarins from the fermentation products of an endophytic fungus of Aspergillus versicolor. Zhou, M. Antiviral and cytotoxic isocoumarin derivatives from an endophytic fungus Aspergillus oryzae.
Planta Medica. Song, R-Y. Isocoumarin derivatives from the endophytic fungus, Pestalotiopsis sp. Fitoterapia , , , Pan, C. Pinchuk, I.
Amicoumacin antibiotic production and genetic diversity of Bacillus subtilis strains isolated from different habitats. Shimojima, Y. Studies on AIs, microbial products with pharmacological activity structures and the chemical nature of AIs. Itoh, J. Isolation, physicochemical properties and biological activities of amicoumacins produced by Bacillus pumilus. Hashimoto, M.
Isolation of phosphate ester derivatives of amicoumacins: structure-activity relationship of hydroxy amino acid moiety. Li, Y. Five new amicoumacins isolated from a marine-derived bacterium Bacillus subtilis.
In the proposed route, a dihydropyran-modified resin is coupled to Merrifield resin and after some steps a polymer-supported bromide is prepared Scheme More complex terpenoids include the sterols. Note 1: Modified from ref. Baxendale, I. Asymmetric reduction of ketimines with trichlorosilane can be catalyzed by N-methylvaline-derived Lewis-basic formamides with high enantioselectivity and low catalyst loading at room temperature in toluene. Synlett , , 29 ,
Drugs , , 10 , Sato, T. A new isocoumarin antibiotic, YM-A.
Canedo, L. Azumi, M.
Bacilosarcins A and B, novel bioactive isocoumarins with unusual heterocyclic cores from the marine-derived bacterium Bacillus subtilis. Tetrahedron , , 64 , Boya, C. Antiplasmodial activity of bacilosarcin A isolated from the octocoral-associated bacterium Bacillus sp. Bioallied Sci. Liu, S.
Tokyo , , 66 , Tokyo , , 69 , Bai, J. Amicoumacins from the marine-derived bacterium Bacillus sp. Tang, H-L. Molecules , , 21 , McInerney, B. Biologically active metabolites from Xenorhabdus spp. Benzopyranone derivatives with gastroprotective activity. Reimer, D. A natural prodrug activation -mechanism in nonribosomal peptide synthesis. Furthermore, traditional research facilities are extremely expensive to commission and run, and yet for a significant proportion of their lives they are under-used or even lying vacant.
To overcome some of these inefficient practices, continuous processing methods such as flow chemistry [ 26 — 32 ] and other enabling technologies [ 16 , 33 — 35 ] are receiving increased attention. With the continuing development of digital imaging technology, computer vision techniques and laboratory automation, some of these routine tasks may be delegated to a computer. And indeed, in cases when our eyes are simply not capable of what is required, for instance, when we would like to observe the contents of a sealed reactor or events outside the visible range of the spectrum, we have no other choice but to rely on camera technology.
The visual data produced are rich in information and can be used to perform complex calculations to make decisions and generate commands in real time. We consider the current state of laboratory decision making to require a human as an interface for allowing a reaction to progress, by performing a workup or a purification, or designing the next experiment Fig. By applying digital cameras and related technologies, this does not always need to be the case: We have identified a number of scenarios in which cameras have been employed by synthetic chemists to aid or enable their work.
In the simplest cases, the camera provides the chemist with a view that would otherwise be inaccessible, or to make a recording of a long experiment to be played back later at a convenient time.